Gene information
Official symbol SIRT5
Official full name sirtuin 5
Gene type protein-coding gene
Chromosome6p23
Gene familySirtuins
Resources
Entrez Gene 23408
HGNC HGNC:14933
Ensembl ENSG00000124523
Vega OTTHUMG00000014278
UCSC uc003nay.4
GO terms: 22 records
GO Description Category LogP Number of genes Detail
GO:0006471 protein ADP-ribosylation GO Biological Processes -3.56106200 4 More
GO:0006476 protein deacetylation GO Biological Processes -5.10714110 7 More
GO:0007005 mitochondrion organization GO Biological Processes -2.05283627 29 More
GO:0009991 response to extracellular stimulus GO Biological Processes -42.2178323 102 More
GO:0010565 regulation of cellular ketone metabolic process GO Biological Processes -15.3155739 32 More
GO:0010656 negative regulation of muscle cell apoptotic process GO Biological Processes -14.6475350 20 More
GO:0010660 regulation of muscle cell apoptotic process GO Biological Processes -26.1774267 35 More
GO:0010662 regulation of striated muscle cell apoptotic process GO Biological Processes -17.3771355 22 More
GO:0010665 regulation of cardiac muscle cell apoptotic process GO Biological Processes -17.8825743 22 More
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO Molecular Functions -7.39079179 12 More
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO Molecular Functions -6.05306731 14 More
GO:0019213 deacetylase activity GO Molecular Functions -6.62830099 7 More
GO:0031667 response to nutrient levels GO Biological Processes -41.8130555 98 More
GO:0033558 protein lysine deacetylase activity GO Molecular Functions -6.90547690 6 More
GO:0034979 NAD-dependent protein deacetylase activity GO Molecular Functions -8.868615 5 More
GO:0035601 protein deacylation GO Biological Processes -4.62709399 7 More
GO:0051287 NAD binding GO Molecular Functions -4.51461289 6 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0070403 NAD+ binding GO Molecular Functions -6.04894404 5 More
GO:0098732 macromolecule deacylation GO Biological Processes -4.47323224 7 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
GO:2000378 negative regulation of reactive oxygen species metabolic process GO Biological Processes -8.33338139 14 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa00760 Nicotinate and nicotinamide metabolism KEGG Pathway -6.71495876 7 More
Drug-Gene interaction
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Related drugs: 6 records
Related studies: 5 records
Molecular factor Omics type Application Objective MI type Reference
NC_000006.12:g.13574131C>A genomics acute myocardial infarction[diagnosis] acute myocardial infarction Chen L et al. Gene. 2018
NC_000006.12:g.13574287G>C genomics acute myocardial infarction[diagnosis] acute myocardial infarction Chen L et al. Gene. 2018
NC_000006.12:g.13573450A>G genomics acute myocardial infarction[diagnosis] acute myocardial infarction Chen L et al. Gene. 2018
NC_000006.12:g.13574110G>A genomics acute myocardial infarction[diagnosis] acute myocardial infarction Chen L et al. Gene. 2018
NC_000006.12:g.13574259G>C genomics acute myocardial infarction[diagnosis] acute myocardial infarction Chen L et al. Gene. 2018
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